September/October 2004 Articles
Editorial
Peptides, Peptidomimetics and Nonpeptides: A Molecular Armamentarium for Basic Research and Drug Development
T.K. Sawyer
Full Text (70K PDF)
News
Cell Fusion to the Rescue
A. Adams
Full Text (47K PDF)
Molecular Neurosurgery for Pain Relief
M.A. Woodbury
Full Text (69K PDF)
Topic Focus: Putting DNA Computers to Work
L. Lederman
Full Text (94K PDF)
Topic Focus: Momentum Builds for Public Clinical Data Registries
S. Redfearn
Full Text (93K PDF)
Myriad Troubles Facing Gene Patents
S. Ghosh
Full Text (46K PDF)
Commentary
Opinion pieces from invited writers on topics of interest to Preclinica readers, such as regulatory guideline clarifications, issues in drug development in academia vs. industry, ethical issues, and specific scientific and preclinical drug development issues.
Regulatory Forum
Impact of the EU Clinical Trials Directive and Other Recent Regulatory Changes on the Manufacture of Biopharmaceuticals
S.D. Jones and H.L. Levine
Full Text (172K PDF)
Regulatory Forum
Clinical Project Management in Central and Eastern Europe
M. Walter and M.J. Bergander
Full Text (174K PDF)
Topic Focus: Meeting the Challenges of Functional Genomics: From the Laboratory to the Clinic
J. Quackenbush
Full Text (119K PDF)
Promise and Reality of Molecular Imaging for Drug Development
J.P. Basilion
Full Text (74K PDF)
Can Preclinical ADMET-PK Now Be Done More Efficiently and Effectively?
C.B. Kissinger and P.T. Kissinger
Full Text (195K PDF)
Leveraging Clinical Knowledge to Fill the Pipeline: A Case Study
G. Tidmarsh
Full Text (133K PDF)
Research Articles
Full peer-reviewed primary data manuscripts covering any of the topics listed in the mission and scope of Preclinica. Includes descriptions of new technical breakthroughs along with "proof-of-concept" data. Review articles on current preclinical technologies and methods are also highlighted.
Review
Terahertz Technology in the Medical and Pharmaceutical Industry
R.M. Woodward
Abstract | Full Text (327K PDF)
Review
Cytochrome c Oxidase Deficiency: From Yeast to Human
A. Solans, A. Zambrano, and A. Barrientos
Abstract | Full Text (573K PDF)
Topic Focus: Automated Classification of Individual Cellular Responses Across Multiple Targets
V.C. Abraham, B. Samson, O. Lapets, and J.R. Haskins
Abstract | Full Text (399K PDF)
Novel Histoculture Drug Response Assay with a Simulated Microgravity Culture System
K. Nakamura, C. Nakahara, H. Kuga, N. Yamanaka, A. Tasaki, H. Nakashima, M. Kubo, T. Morisaki, H. Fujii, K. Sueishi, M. Tanaka, and M. Katano
Abstract | Full Text (468K PDF)
Special Feature
Selected Abstracts from Drug Discovery Technology®
Abstract | Full Text (348K PDF)
Products and Services
New Products and Services for Preclinical Development
Full Text (71K PDF)
