September/October 2003 Articles
Editorial
Ethics and Gene Therapy
P.R. Reilly
Full Text (61K PDF)
News
The Best Mouse Model Yet for Human Heart Disease?
J. Alper
Full Text (84K PDF)
Small Molecule Therapy Revisited: A One-Two Punch for Cystic Fibrosis?
J. Ashkenas
Full Text (107K PDF)
Targeting Co-Stimulation: Human Cancer Vaccines Tread New and Perilous Ground
J. Ashkenas
Full Text (61K PDF)
New Directions for Oncolytic Virus Design
A. DePalma
Full Text (94K PDF)
Prion Disease Detection: A Conformation-Sensitive Antibody Makes Its Mark
K. Kleiner
Full Text (62K PDF)
MIAME or Bust: Realizing the Promise of Microarray Data
B. Reid
Full Text (67K PDF)
Venture Capital 2003: A Rising Tide that Lifts Only the Largest Boats
S. Redfearn
Full Text (89K PDF)
Quick Drug Approval for Serious Diseases
M. Fogarty
Full Text (99K PDF)
Commentary
Opinion pieces from invited writers on topics of interest to Preclinica readers, such as regulatory guideline clarifications, issues in drug development in academia vs. industry, ethical issues, and specific scientific and preclinical drug development issues.
Regulatory Forum
Genetic Testing and Personalized Medicine: An FDA View
E. Mansfield
Full Text (87K PDF)
The Biotechnology Initiative in the USP
R. Dabbah
Full Text (49K PDF)
Process Biology: Managing Information Flow for Improved Decision Making in Preclinical R&D
J.F. Reidhaar-Olson, H. Ohkawa, L.E. Babiss, and J. Hammer
Full Text (312K PDF)
Avoid Barriers and Reduce Preclinical Development Time by Working with an Integrated Multifocus CRO Partner
K.P. Plotzke
Full Text (149K PDF)
Contract Research Organizations Offering Preclinical Services
Full Text (85K PDF)
Research Articles
Full peer-reviewed primary data manuscripts covering any of the topics listed in the mission and scope of Preclinica. Includes descriptions of new technical breakthroughs along with "proof-of-concept" data. Review articles on current preclinical technologies and methods are also highlighted.
Preclinical Studies of Anticancer Efficacy of 5-Fluorouracil when Co-Administered with the 1,4-ß-D-Galactomannan
A.A. Klyosov, D. Platt, and E. Zomer
Abstract | Full Text (346K PDF)
Variations in Backbone and Promoters in Recombinant Adenoviruses Expressing Human p21WAF1/Cip1 for Potential Use in Ocular Gene Therapy
K.N. Wills, J.B. Avanzini, I. Atencio, S.F. Wen, J. Shinoda, M. Ni, J.A. Howe, D. Antelman, S. Sutjipto, and B. Faha
Abstract | Full Text (332K PDF)
Review
Delivery of Plasmid DNA Using In Vivo Electroporation
R. Heller
Abstract | Full Text (234K PDF)
Special Feature
Selected Abstracts from Drug Discovery Technology® World Congress
Abstract | Full Text (106K PDF)
Products and Services
New Products and Services for Preclinical Development
Full Text (70K PDF)
