May/June 2003 Articles
Editorial
Finding the Preclinical Thread in Scientific Diversity
B. VanRenterghem
Full Text (78K PDF)
News
Putting Viruses at RISC: RNA Interference Inches Toward the Clinic
J. Ashkenas
Full Text (79K PDF)
Gene Therapy on the SCIDs
C. Smith
Full Text (157K PDF)
Official Responses to 'Adverse Events' in the X-SCID Trial
G. Miller
Full Text (55K PDF)
Monkey Trials: Can We Afford to Follow Through on Primate Studies?
B. Reid
Full Text (64K PDF)
NSAIDS and Alzheimer's Disease: Novel Roles for Some Familiar Drugs
M. Fogarty
Full Text (74K PDF)
Antibody Therapy for Food Allergies: A Tough Nut to Crack
A. DePalma
Full Text (92K PDF)
Prospects for Genomic Medicine: The Tough Case of Mitochondrial Diseases
J. Ashkenas
Full Text (123K PDF)
FDA Develops Computer-Aided Toxicology Screen
J. Alper
Full Text (67K PDF)
Can We Leave Tumor Antigens Undefined?
J. Ashkenas
Full Text (63K PDF)
Dendritic Cells Grow Sour with Age
M.A. Woodbury
Full Text (58K PDF)
Commentary
Opinion pieces from invited writers on topics of interest to Preclinica readers, such as regulatory guideline clarifications, issues in drug development in academia vs. industry, ethical issues, and specific scientific and preclinical drug development issues.
G Protein-Coupled Receptors: A View from the Sidelines
M.J. Brownstein
Full Text (106K PDF)
Predictive Toxicology Technology for Avoiding Idiosyncratic Liver Injury
C. Alden, J. Lin, and P. Smith
Full Text (222K PDF)
Two-Hybrid Proteomics: Leveraging Small-Scale Proteomic Techniques to Take Advantage of Large-Scale Databases
M. Gillespie
Abstract | Full Text (166K PDF)
Harmonization of Compendial Procedures
R. Dabbah
Full Text (57K PDF)
Getting Off to a Clean Start With Presterilized Single-Use Filters
H. Haughney
Full Text (148K PDF)
Children of the Rib: How Potent Are Adult Stem Cells?
M. J. Brownstein and É. Mezey
Full Text (89K PDF)
Research Articles
Full peer-reviewed primary data manuscripts covering any of the topics listed in the mission and scope of Preclinica. Includes descriptions of new technical breakthroughs along with "proof-of-concept" data. Review articles on current preclinical technologies and methods are also highlighted.
Extended S+/L- Assay for Detecting Replication-Competent Retroviruses Pseudotyped with the RD114 Viral Envelope
L. Duffy, S. Koop, J. Fyffe, and K. Cornetta
Abstract | Full Text (198K PDF)
Modifications of the Cholesterol-Fed Rabbit Model of Atherosclerosis Using Diets with Different Levels of Cholesterol Supplementation
L.J. Thomas, M.D. Picard, D.P. Miller, H. Adari, D.T. Beattie, C.D. Emmett, C.W. Rittershaus, and C.L. Pettey
Abstract | Full Text (215K PDF)
Products and Services
New Products and Services for Preclinical Development
Full Text (69K PDF)
